Peep Show series 9 get here already!
SCIENTIFIC ILLUSTRATION: Nucleosome
The Mediterranean Institute for Life Sciences
High resolution ray-traced model of a nucleosome, isolated on black.
A nucleosome is the basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around four histone protein cores. This structure is often compared to thread wrapped around a spool.
Nucleosomes form the fundamental repeating units of eukaryotic chromatin, which is used to pack the large eukaryotic genomes into the nucleus while still ensuring appropriate access to it. In mammalian cells approximately 2 m of linear DNA have to be packed into a nucleus of roughly 10 µm diameter.
Nucleosomes are folded through a series of successively higher order structures to eventually form a chromosome; this both compacts DNA and creates an added layer of regulatory control, which ensures correct gene expression.
How do you say hi to someone who makes your gut feel like it’s being hugged and stabbed at the same time?
PHOTO RECAP | The Vampire Diaries 4x21: She Gets Better
Hey what’s going on you guys! If you’re anything like me you’ve spent the last three months trapped in a steel drum rolling down an “up” escalator. Life can be very dizzying and loud and it’s like nobody will help you because there is a sale at Chico’s. But here we are again, talking about the best show on television Monster Mashin’. Just kidding it’s actually called The Vampire Diaries and A METRIC TON has happened since last time we hung out on the internet together gabbin’ about it. Here’s a quick list of highlights: